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Tocilizumab Contributes to the Inflammatory Status of Mature Dendritic Cells through Interleukin-6 Receptor Subunits Modulation

Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid arthritis (RA) and the systemic form of juvenile idiopathic arthritis in children. Its indications are expected to be largely extended to other infla...

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Autori principali: Daniel Meley, Audrey Héraud, Valerie Gouilleux-Gruart, Fabrice Ivanes, Florence Velge-Roussel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017-08-01
Serie:Frontiers in Immunology
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Accesso online:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00926/full
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