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Tocilizumab Contributes to the Inflammatory Status of Mature Dendritic Cells through Interleukin-6 Receptor Subunits Modulation

Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid arthritis (RA) and the systemic form of juvenile idiopathic arthritis in children. Its indications are expected to be largely extended to other infla...

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Autores principales: Daniel Meley, Audrey Héraud, Valerie Gouilleux-Gruart, Fabrice Ivanes, Florence Velge-Roussel
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017-08-01
Colección:Frontiers in Immunology
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Acceso en línea:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00926/full
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