High molecular weight insoluble parkin in the substantia nigra of patients with idiopathic Parkinson’s disease

Abstract Parkinson’s disease (PD) is characterized by a loss of dopaminergic neurons and accumulation of α-synuclein (α-syn)-containing Lewy bodies in the substantia nigra (SN) pars compacta. Mutations in the gene coding for the protein parkin cause a form of autosomal recessive juvenile parkinsonis...

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Váldodahkkit:	Cyntia Tremblay, Laura Pshevorskiy, Rosalie J. Cottez, Hélèna L. Denis, Vincent Emond, Marc Morissette, Ali H. Rajput, Thérèse Di Paolo, Alex Rajput, Frédéric Calon
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Portfolio 2026-05-01
Ráidu:	npj Parkinson's Disease
Liŋkkat:	https://doi.org/10.1038/s41531-026-01371-2
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