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Inhibition of CXXC5 function rescues Alzheimer’s disease phenotypes by restoring Wnt/β-catenin signaling pathway

Alzheimer’s disease (AD) is the most prevalent type of dementia and is characterized by cognitive deficits and accumulation of pathological plaques. Owing to the complexity of AD development, paradigms for AD research and drug discovery have shifted to target factors that mediate multiple pathogenes...

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Autors principals: Minguen Yoon, Heejene Kim, Heewon Shin, HeeYang Lee, Min-Jeong Kang, Sung-Hye Park, Gyoonhee Han, YoungSoo Kim, Kang-Yell Choi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2023-08-01
Col·lecció:Pharmacological Research
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S1043661823001925
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