Sequence- and structure-specific RNA oligonucleotide binding attenuates heterogeneous nuclear ribonucleoprotein A1 dysfunction

The RNA binding protein heterogeneous nuclear ribonucleoprotein A1 (A1) regulates RNA metabolism, which is crucial to maintaining cellular homeostasis. A1 dysfunction mechanistically contributes to reduced cell viability and loss, but molecular mechanisms of how A1 dysfunction affects cell viability...

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Principais autores:	Joseph P. Clarke, Patricia A. Thibault, Sakina Fatima, Hannah E. Salapa, Subha Kalyaanamoorthy, Aravindhan Ganesan, Michael C. Levin
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2023-06-01
Series:	Frontiers in Molecular Biosciences
Assuntos:	hnRNPA1 RNA oligonucleotide optogenetics stress granules RNA-protein interaction
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1178439/full
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