CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells

Summary: CTCF/cohesin-binding sites (CBSs) at the chromatin-loop anchors and topologically associating domains are frequently mutated in cancer; however, the underlying molecular mechanisms remain unclear. Here, we investigate whether CTCF and cohesin co-binding on DNA imposes constraints on DNA rep...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Elangoli Ebrahimkutty Faseela, Dimple Notani, Radhakrishnan Sabarinathan
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2026-02-01
Sarja:	iScience
Aiheet:	Cell biology Bioinformatics Cancer
Linkit:	http://www.sciencedirect.com/science/article/pii/S2589004226000210
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