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Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia

The NLRP3 inflammasome has been reported to be activated by atherogenic factors, whereby endothelial injury and consequent atherosclerotic lesions are triggered in the arterial wall. However, the mechanisms activating and regulating NLRP3 inflammasomes remain poorly understood. The present study tes...

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Principais autores: Saisudha Koka, Min Xia, Yang Chen, Owais M. Bhat, Xinxu Yuan, Krishna M. Boini, Pin-Lan Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-10-01
coleção:Redox Biology
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231717303610
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