Frk positively regulates innate antiviral immunity by phosphorylating TBK1

Type I interferons (IFN-I) are crucial for the initial defense against viral infections. TBK1 serves as a key regulator in the production of IFN-I, with its phosphorylation being essential for the regulation of its activity. However, the regulatory mechanisms governing its activation remain incomple...

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Autors principals:	Xiaomei Zhang, Ying You, Tingrong Xiong, Xiaokai Zhang, Haibo Wang, Jinxia Geng, Miao Wang, Yanyan Xu, Shanshan Gao, Xiaoyan Wu, Yue Zheng, Xianhua Wen, Haoyu Yang, Yu Wang, Xiaohua Wen, Congcong Zhao
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-02-01
Col·lecció:	Frontiers in Microbiology
Matèries:	macrophages Frk TBK1 phosphorylation IFN-I
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1525648/full
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