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Nanoscale Reaction Vessels Designed for Synthesis of Copper-Drug Complexes Suitable for Preclinical Development.

The development of copper-drug complexes (CDCs) is hindered due to their very poor aqueous solubility. Diethyldithiocarbamate (DDC) is the primary metabolite of disulfiram, an approved drug for alcoholism that is being repurposed for cancer. The anticancer activity of DDC is dependent on complexatio...

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Váldodahkkit: Mohamed Wehbe, Malathi Anantha, Ian Backstrom, Ada Leung, Kent Chen, Armaan Malhotra, Katarina Edwards, Marcel B Bally
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2016-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC4824478?pdf=render
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