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High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells

Abstract Background Human mesenchymal stem cells (hMSCs) are intensely researched for applications in cell therapeutics due to their unique properties, however, intrinsic therapeutic properties of hMSCs could be enhanced by genetic modification. Viral transduction is efficient, but suffers from safe...

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Huvudupphov: Tyler Kozisek, Andrew Hamann, Albert Nguyen, Michael Miller, Sarah Plautz, Angela K. Pannier
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2020-05-01
Serie:Journal of Biological Engineering
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Länkar:http://link.springer.com/article/10.1186/s13036-020-00238-1
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