Systematic comparison of nonviral gene delivery strategies for efficient co-expression of two transgenes in human mesenchymal stem cells

Abstract Background Human mesenchymal stem cells (hMSCs) are being researched for cell-based therapies due to a host of unique properties, however, genetic modification of hMSCs, accomplished through nonviral gene delivery, could greatly advance their therapeutic potential. Furthermore, expression o...

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Bibliografiske detaljer

Principais autores:	Tyler Kozisek, Luke Samuelson, Andrew Hamann, Angela K. Pannier
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2023-12-01
Serier:	Journal of Biological Engineering
Fag:	Human mesenchymal stem cells Transfection Lipid-mediated transfection Polymer-mediated transfection 2A peptide sequence IRES
Online adgang:	https://doi.org/10.1186/s13036-023-00394-0
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