Côd QR

An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8+ T cells

Dendritic cell (DC)-maturation stimuli determine the potency of these antigen-presenting cells and, therefore, the quality of the T-cell response. Here we describe that the maturation of DCs via TriMix mRNA, encoding CD40 ligand, a constitutively active variant of toll-like receptor 4 and the co-sti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Prif Awduron: Wout de Mey, Hanne Locy, Kirsten De Ridder, Phaedra De Schrijver, Dorien Autaers, Asma Lakdimi, Arthur Esprit, Lorenzo Franceschini, Kris Thielemans, Magali Verdonck, Karine Breckpot
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2023-02-01
Cyfres:Frontiers in Immunology
Pynciau:
cancer
CD40 ligand
dendritic cell
interferon-gamma
interleukin-10
interleukin-12
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1111523/full
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg