Switching of hypertrophic signalling towards enhanced cardiomyocyte identity and maturity by a GATA4-targeted compound

Abstract Background The prevalence of heart failure is constantly increasing, and the prognosis of patients remains poor. New treatment strategies to preserve cardiac function and limit cardiac hypertrophy are therefore urgently needed. Human induced pluripotent stem cell-derived cardiomyocytes (hiP...

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Xehetasun bibliografikoak

Egile Nagusiak:	Lotta Pohjolainen, Sini M. Kinnunen, Samuli Auno, Alexandros Kiriazis, Saana Pohjavaara, Julia Kari-Koskinen, Matej Zore, Mikael Jumppanen, Jari Yli-Kauhaluoma, Virpi Talman, Heikki Ruskoaho, Mika J. Välimäki
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2024-01-01
Saila:	Stem Cell Research & Therapy
Gaiak:	Cardiomyocytes Maturation Hypertrophy GATA4 Isoxazole derivatives
Sarrera elektronikoa:	https://doi.org/10.1186/s13287-023-03623-x
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