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Carboxy-terminal mutations of bile acid CoA:N-acyltransferase alter activity and substrate specificity

Bile acid CoA:amino acid N-acyltransferase (BAAT) is the terminal enzyme in the synthesis of bile salts from cholesterol and catalyzes the conjugation of taurine or glycine to bile acid CoA thioesters to form bile acid N-acylamidates. BAAT has a dual localization to the cytosol and peroxisomes, poss...

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主要な著者: Nathan A. Styles, Erin M. Shonsey, Josie L. Falany, Amber L. Guidry, Stephen Barnes, Charles N. Falany
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2016-07-01
シリーズ:Journal of Lipid Research
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S0022227520351518
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