A novel method for cell deconvolution using DNA methylation in PCA space

Abstract Background In this study, we present a novel method for reference-based cell deconvolution using data from DNA methylation arrays. Different from existing methods like IDOL-Ext, which operate on probe-level data, our approach represents features in the principal component analysis (PCA) spa...

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Hlavní autoři:	Huan Xu, Ge Zhang, Jing Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-08-01
Edice:	BMC Genomics
Témata:	DNA methylation Cell deconvolution Bioinformatics Principal component analysis
On-line přístup:	https://doi.org/10.1186/s12864-024-10652-0
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