Down Syndrome Altered Cell Composition in Blood, Brain, and Buccal Swab Samples Profiled by DNA-Methylation-Based Cell-Type Deconvolution

Down syndrome (DS) is a genetic disorder caused by an extra copy of chromosome 21 that presents developmental dysfunction and intellectual disability. To better understand the cellular changes associated with DS, we investigated the cell composition in blood, brain, and buccal swab samples from DS p...

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Principais autores:	Ze Zhang, Hannah G. Stolrow, Brock C. Christensen, Lucas A. Salas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-04-01
coleção:	Cells
Assuntos:	down syndrome trisomy 21 DNA methylation cell deconvolution epigenetics immune cell deconvolution
Acesso em linha:	https://www.mdpi.com/2073-4409/12/8/1168
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