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Glioma immune microenvironment composition calculator (GIMiCC): a method of estimating the proportions of eighteen cell types from DNA methylation microarray data

Abstract A scalable platform for cell typing in the glioma microenvironment can improve tumor subtyping and immune landscape detection as successful immunotherapy strategies continue to be sought and evaluated. DNA methylation (DNAm) biomarkers for molecular classification of tumor subtypes have bee...

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Principais autores: Steven C. Pike, John K. Wiencke, Ze Zhang, Annette M. Molinaro, Helen M. Hansen, Devin C. Koestler, Brock C. Christensen, Karl T. Kelsey, Lucas A. Salas
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2024-10-01
סדרה:Acta Neuropathologica Communications
נושאים:
Glioma
DNA methylation
Tumor microenvironment
Epidemiology
Deconvolution
גישה מקוונת:https://doi.org/10.1186/s40478-024-01874-0
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