Stress fiber strain is zero in normal aortic smooth muscle, elevated in hypertensive stretch, and minimal in wall thickening rats

Abstract Hypertension causes aortic wall thickening until the original wall stress is restored. We hypothesized that this regulation involves stress fiber (SF) tension transmission to the nucleus in smooth muscle cells (SMCs) and investigated the strain in the SF direction as a condition required fo...

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Detalhes bibliográficos

Principais autores:	Shukei Sugita, Rintaro Kawai, Yoshihiro Ujihara, Masanori Nakamura
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-11-01
Colecção:	Scientific Reports
Assuntos:	Hypertension Fluorescent microscopy Vascular smooth muscle cells Stress fiber Normal strain
Acesso em linha:	https://doi.org/10.1038/s41598-024-81229-w
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