Stress fiber strain is zero in normal aortic smooth muscle, elevated in hypertensive stretch, and minimal in wall thickening rats

Abstract Hypertension causes aortic wall thickening until the original wall stress is restored. We hypothesized that this regulation involves stress fiber (SF) tension transmission to the nucleus in smooth muscle cells (SMCs) and investigated the strain in the SF direction as a condition required fo...

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Ngā kaituhi matua:	Shukei Sugita, Rintaro Kawai, Yoshihiro Ujihara, Masanori Nakamura
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2024-11-01
Rangatū:	Scientific Reports
Ngā marau:	Hypertension Fluorescent microscopy Vascular smooth muscle cells Stress fiber Normal strain
Urunga tuihono:	https://doi.org/10.1038/s41598-024-81229-w
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Stress fiber strain is zero in normal aortic smooth muscle, elevated in hypertensive stretch, and minimal in wall thickening rats

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