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Tumour catabolism independent of malnutrition and inflammation in upper GI cancer patients revealed by longitudinal metabolomics

Abstract Background The detrimental impact of malnutrition and cachexia in cancer patients subjected to surgical resection is well established. However, how systemic and local metabolic alterations in cancer patients impact the serum metabolite signature, thereby leading to cancer‐specific differenc...

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Principais autores: Janusz vonRenesse, Felix vonBechtolsheim, Sophie Jonas, Lena Seifert, Tiago C. Alves, Adrian M. Seifert, Filip Komorek, Guergana Tritchkova, Mario Menschikowski, Ulrich Bork, Ronny Meisterfeld, Marius Distler, Triantafyllos Chavakis, Jürgen Weitz, Alexander M. Funk, Christoph Kahlert, Peter Mirtschink
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2023-02-01
coleção:Journal of Cachexia, Sarcopenia and Muscle
Assuntos:
NMR
Gastrointestinal cancer
Metabolic profile
Metabolome
Ketone bodies
3‐Hydroxybutyrate
Acesso em linha:https://doi.org/10.1002/jcsm.13131
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