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Tumour catabolism independent of malnutrition and inflammation in upper GI cancer patients revealed by longitudinal metabolomics

Abstract Background The detrimental impact of malnutrition and cachexia in cancer patients subjected to surgical resection is well established. However, how systemic and local metabolic alterations in cancer patients impact the serum metabolite signature, thereby leading to cancer‐specific differenc...

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Автори: Janusz vonRenesse, Felix vonBechtolsheim, Sophie Jonas, Lena Seifert, Tiago C. Alves, Adrian M. Seifert, Filip Komorek, Guergana Tritchkova, Mario Menschikowski, Ulrich Bork, Ronny Meisterfeld, Marius Distler, Triantafyllos Chavakis, Jürgen Weitz, Alexander M. Funk, Christoph Kahlert, Peter Mirtschink
Формат: Artigo
Мова:Inglês
Опубліковано: Wiley 2023-02-01
Серія:Journal of Cachexia, Sarcopenia and Muscle
Предмети:
NMR
Gastrointestinal cancer
Metabolic profile
Metabolome
Ketone bodies
3‐Hydroxybutyrate
Онлайн доступ:https://doi.org/10.1002/jcsm.13131
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