Opioid Facilitation of β-Adrenergic Blockade: A New Pharmacological Condition?

Recently, propranolol was suggested to prevent hyperlactatemia in a child with hypovolemic shock through β-adrenergic blockade. Though it is a known inhibitor of glycolysis, propranolol, outside this observation, has never been reported to fully protect against lactate overproduction. On the other h...

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Autors principals:	Joseph Vamecq, Karine Mention-Mulliez, Francis Leclerc, Dries Dobbelaere
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2015-09-01
Col·lecció:	Pharmaceuticals
Matèries:	lactate glycolysis disruption Na+/K+ ATPase β-adrenergic receptor G protein cAMP protein kinase A shock δ-opioid receptor
Accés en línia:	http://www.mdpi.com/1424-8247/8/4/664
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