Effects of canagliflozin on myocardial microvascular density, oxidative stress, and proteomic profile

Introduction: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are cardioprotective, and canagliflozin (CANA), an SGLT2i, has been shown to improve perfusion, AMPK signaling, and oxidative stress in chronically ischemic myocardium. The aim of this study is to determine the effects of CANA in nonis...

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Detalhes bibliográficos

Principais autores:	Sharif A. Sabe, Cynthia M. Xu, Mohamed Sabra, Dwight D. Harris, Mark Broadwin, Krishna G. Bellam, Debolina Banerjee, Anny Usheva, M. Ruhul Abid, Frank W. Sellke
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-12-01
coleção:	Journal of Molecular and Cellular Cardiology Plus
Assuntos:	Angiogenesis Coronary microvasculature Proteomics SGLT2i
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2772976123000223
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