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Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells

Bone sarcomas are heterogeneous malignant tumors that exhibit clinical, histological, and molecular heterogeneity. Recent progress in their multimodal treatment has gradually improved patient prognosis; however, drug resistance and distant metastasis remain unresolved clinical problems. Recent inves...

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Detalhes bibliográficos
Main Authors: Tomohiro Fujiwara, Toshifumi Ozaki
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2016-01-01
Colecção:Stem Cells International
Acesso em linha:http://dx.doi.org/10.1155/2016/2603092
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