Relationships between genome-wide R-loop distribution and classes of recurrent DNA breaks in neural stem/progenitor cells

Abstract Recent studies revealed classes of recurrent DNA double-strand breaks (DSBs) in neural stem/progenitor cells, including transcription-associated, promoter-proximal breaks and recurrent DSB clusters in late-replicating, long neural genes that may give rise to somatic brain mosaicism. The mec...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Supawat Thongthip, Annika Carlson, Magdalena P. Crossley, Bjoern Schwer
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2022-08-01
Rangatū:	Scientific Reports
Urunga tuihono:	https://doi.org/10.1038/s41598-022-17452-0
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!