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A feasibility of computational drug screening for Fuchs endothelial corneal dystrophy

Abstract Fuchs endothelial corneal dystrophy (FECD) remains a leading cause of corneal blindness globally, with corneal transplantation being the primary treatment. FECD is characterized by the formation of guttae, extracellular matrix (ECM) deposits beneath the corneal endothelium, and progressive...

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Bibliografische gegevens
Hoofdauteurs: Itsuki Oka, Yoshiaki Toyokawa, Kouta Imai, Tatsuya Nakagawa, Theofilos Tourtas, Ursula Schlötzer-Schrehardt, Friedrich Kruse, Noriko Koizumi, Naoki Okumura
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2025-04-01
Reeks:Scientific Reports
Online toegang:https://doi.org/10.1038/s41598-025-95003-z
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