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Molecular Dynamics Simulations Predict that rSNP Located in the <i>HNF-1α</i> Gene Promotor Region Linked with MODY3 and Hepatocellular Carcinoma Promotes Stronger Binding of the HNF-4α Transcription Factor

Our study aims to investigate the impact of the Maturity-onset diabetes of the young 3 disease-linked rSNP rs35126805 located in the <i>HNF-1α</i> gene promotor on the binding of the transcription factor HNF-4α and consequently on the regulation of <i>HNF-1α</i> gene expression. Our focus is to calc...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Eva Španinger, Uroš Potočnik, Urban Bren
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: MDPI AG 2020-12-01
Цуврал:Biomolecules
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/2218-273X/10/12/1700
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