Molecular Dynamics Simulations Predict that rSNP Located in the <i>HNF-1α</i> Gene Promotor Region Linked with MODY3 and Hepatocellular Carcinoma Promotes Stronger Binding of the HNF-4α Transcription Factor
Our study aims to investigate the impact of the Maturity-onset diabetes of the young 3 disease-linked rSNP rs35126805 located in the <i>HNF-1α</i> gene promotor on the binding of the transcription factor HNF-4α and consequently on the regulation of <i>HNF-1α</i> gene expression. Our focus is to calc...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2020-12-01
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| Col·lecció: | Biomolecules |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/2218-273X/10/12/1700 |
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