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The long noncoding RNA TARID regulates the CXCL3/ERK/MAPK pathway in trophoblasts and is associated with preeclampsia

Abstract Background The widely accepted explanation of preeclampsia (PE) pathogenesis is insufficient trophoblast invasion and impaired uterine spiral artery remodeling. However, the underlying molecular mechanism remains unclear. Methods We performed transcriptome sequencing on placentas of normal...

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Autori principali: Lingyun Liao, Min Liu, Yijie Gao, Xiaohong Wei, Yangxue Yin, Linbo Gao, Rong Zhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-11-01
Serie:Reproductive Biology and Endocrinology
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Accesso online:https://doi.org/10.1186/s12958-022-01036-8
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