Rigosertib inhibits MEK1–ERK pathway and alleviates lipopolysaccharide‐induced sepsis
Abstract Background Here, by using the lipopolysaccharide (LPS)‐induced mice sepsis model, we treated septic wild‐type (WT) mice or MEK1DD mice with rigosertib to evaluate its prospective effects on sepsis. Methods We also generated macrophages derived from bone marrow from WT or MEK1DD mice. These...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2021-09-01
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| Colecção: | Immunity, Inflammation and Disease |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/iid3.458 |
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