Design and Engineering of Light‐Induced Base Editors Facilitating Genome Editing with Enhanced Fidelity
Abstract Base editors, which enable targeted locus nucleotide conversion in genomic DNA without double‐stranded breaks, have been engineered as powerful tools for biotechnological and clinical applications. However, the application of base editors is limited by their off‐target effects. Continuously...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley
2024-02-01
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| Schriftenreihe: | Advanced Science |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1002/advs.202305311 |
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