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Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia

Abstract Background Tissue stem cells are confined within a special microenvironment called niche. Stem cells in such a niche are supplied with nutrients and contacted by other cells to maintain their characters and also to keep or expand their population size. Besides, oxygen concentration is a key...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Taichi Kashiwagi, Yuuki Takazawa, Tetsushi Kagawa, Tetsuya Taga
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-02-01
Schriftenreihe:Inflammation and Regeneration
Schlagworte:
neural stem/progenitor cells
NSPC niche
self-organization
autocrine
hypoxia
vascular endothelial growth factor
Online-Zugang:https://doi.org/10.1186/s41232-022-00254-2
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