Ricolinostat promotes the generation of megakaryocyte progenitors from human hematopoietic stem and progenitor cells

Abstract Background Ex vivo production of induced megakaryocytes (MKs) and platelets from stem cells is an alternative approach for supplying transfusible platelets. However, it is difficult to generate large numbers of MKs and platelets from hematopoietic stem cells and progenitor cells (HSPCs). Me...

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Detalhes bibliográficos

Principais autores:	Jianan Jiang, Jinhua Qin, Jisheng Li, Xiaosong Lin, Bowen Zhang, Zeng Fan, Lijuan He, Quan Zeng, Wen Yue, Min Zheng, Xuetao Pei, Yanhua Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-02-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Ricolinostat Hematopoietic stem and progenitor cell Megakaryocyte progenitor Megakaryocyte
Acesso em linha:	https://doi.org/10.1186/s13287-022-02722-5
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