Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia

Abstract Background Tissue stem cells are confined within a special microenvironment called niche. Stem cells in such a niche are supplied with nutrients and contacted by other cells to maintain their characters and also to keep or expand their population size. Besides, oxygen concentration is a key...

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Autori principali:	Taichi Kashiwagi, Yuuki Takazawa, Tetsushi Kagawa, Tetsuya Taga
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-02-01
Serie:	Inflammation and Regeneration
Soggetti:	neural stem/progenitor cells NSPC niche self-organization autocrine hypoxia vascular endothelial growth factor
Accesso online:	https://doi.org/10.1186/s41232-022-00254-2
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