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An attenuated quadruple gene mutant of Mycobacterium tuberculosis imparts protection against tuberculosis in guinea pigs

Previously we had developed a triple gene mutant of Mycobacterium tuberculosis (MtbΔmms) harboring disruption in three genes, namely mptpA, mptpB and sapM. Though vaccination with MtbΔmms strain induced protection in the lungs of guinea pigs, the mutant strain failed to control the hematogenous spre...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ritika Kar Bahal, Shubhita Mathur, Priyanka Chauhan, Anil K. Tyagi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: The Company of Biologists 2018-01-01
Rangatū:Biology Open
Ngā marau:
Urunga tuihono:http://bio.biologists.org/content/7/1/bio029546
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