Nanoparticles With Affinity for α-Synuclein Sequester α-Synuclein to Form Toxic Aggregates in Neurons With Endolysosomal Impairment
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. It is characterized pathologically by the aggregation of α-synuclein (αS) in the form of Lewy bodies and Lewy neurites. A major challenge in PD therapy is poor efficiency of drug delivery to the brain due to the blood–bra...
Guardat en:
| Autors principals: | , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2021-10-01
|
| Col·lecció: | Frontiers in Molecular Neuroscience |
| Matèries: | |
| Accés en línia: | https://www.frontiersin.org/articles/10.3389/fnmol.2021.738535/full |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|