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Accelerated DNA methylation age plays a role in the impact of cardiovascular risk factors on the human heart

Abstract Background DNA methylation (DNAm) age acceleration (AgeAccel) and cardiac age by 12-lead advanced electrocardiography (A-ECG) are promising biomarkers of biological and cardiac aging, respectively. We aimed to explore the relationships between DNAm age and A-ECG heart age and to understand...

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Principais autores: Constantin-Cristian Topriceanu, Eesha Dev, Mahmood Ahmad, Rebecca Hughes, Hunain Shiwani, Matthew Webber, Kenan Direk, Andrew Wong, Martin Ugander, James C. Moon, Alun D. Hughes, Jane Maddock, Todd T. Schlegel, Gabriella Captur
格式: Artigo
语言:Inglês
出版: BMC 2023-10-01
丛编:Clinical Epigenetics
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在线阅读:https://doi.org/10.1186/s13148-023-01576-9
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