Accelerated DNA methylation age plays a role in the impact of cardiovascular risk factors on the human heart

Abstract Background DNA methylation (DNAm) age acceleration (AgeAccel) and cardiac age by 12-lead advanced electrocardiography (A-ECG) are promising biomarkers of biological and cardiac aging, respectively. We aimed to explore the relationships between DNAm age and A-ECG heart age and to understand...

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Autores principales:	Constantin-Cristian Topriceanu, Eesha Dev, Mahmood Ahmad, Rebecca Hughes, Hunain Shiwani, Matthew Webber, Kenan Direk, Andrew Wong, Martin Ugander, James C. Moon, Alun D. Hughes, Jane Maddock, Todd T. Schlegel, Gabriella Captur
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-10-01
Colección:	Clinical Epigenetics
Materias:	Advanced electrocardiography Aging DNA methylation age
Acceso en línea:	https://doi.org/10.1186/s13148-023-01576-9
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