Intracellular VHHs to monitor and modulate GPCR signaling

Single-domain antibody fragments, also known as VHHs or nanobodies, have opened promising avenues in therapeutics and in exploration of intracellular processes. Because of their unique structural properties, they can reach cryptic regions in their cognate antigen. Intracellular VHHs/antibodies prima...

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書誌詳細

主要な著者:	Pauline Raynaud, Camille Gauthier, Vinesh Jugnarain, Frédéric Jean-Alphonse, Eric Reiter, Gilles Bruneau, Pascale Crépieux
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2022-11-01
シリーズ:	Frontiers in Endocrinology
主題:	G protein-coupled receptor conformations intracellular VHHs Cell signaling G proteins β-arrestins
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fendo.2022.1048601/full
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