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Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation

High mobility group box 1 protein (HMGB1), a highly conserved nuclear DNA-binding protein, is a “damage-associated molecular pattern” molecule (DAMP) implicated in both stimulating and inhibiting innate immunity. As reviewed here, HMGB1 is an oxidation-reduction sensitive DAMP bearing three cysteine...

詳細記述

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書誌詳細
主要な著者: Ulf Andersson, Kevin J. Tracey, Huan Yang
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2021-11-01
シリーズ:Cells
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/10/12/3323
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