Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation
High mobility group box 1 protein (HMGB1), a highly conserved nuclear DNA-binding protein, is a “damage-associated molecular pattern” molecule (DAMP) implicated in both stimulating and inhibiting innate immunity. As reviewed here, HMGB1 is an oxidation-reduction sensitive DAMP bearing three cysteine...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2021-11-01
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| coleção: | Cells |
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| Acesso em linha: | https://www.mdpi.com/2073-4409/10/12/3323 |
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