DNA Damage Tolerance Pathways in Human Cells: A Potential Therapeutic Target
DNA lesions arising from both exogenous and endogenous sources occur frequently in DNA. During DNA replication, the presence of unrepaired DNA damage in the template can arrest replication fork progression, leading to fork collapse, double-strand break formation, and to genome instability. To facili...
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| Huvudupphov: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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Frontiers Media S.A.
2022-02-01
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| Serie: | Frontiers in Oncology |
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| Länkar: | https://www.frontiersin.org/articles/10.3389/fonc.2021.822500/full |
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