Retargeting azithromycin analogues to have dual-modality antimalarial activity
Abstract Background Resistance to front-line antimalarials (artemisinin combination therapies) is spreading, and development of new drug treatment strategies to rapidly kill Plasmodium spp. malaria parasites is urgently needed. Azithromycin is a clinically used macrolide antibiotic proposed as a par...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-09-01
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| coleção: | BMC Biology |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12915-020-00859-4 |
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