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Antibody Targets and Properties for Complement-Fixation Against the Circumsporozoite Protein in Malaria Immunity

The Plasmodium falciparum circumsporozoite protein (CSP) forms the basis of leading subunit malaria vaccine candidates. However, the mechanisms and specific targets of immunity are poorly defined. Recent findings suggest that antibody-mediated complement-fixation and activation play an important rol...

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Príomhchruthaitheoirí: Liriye Kurtovic, Damien R. Drew, Arlene E. Dent, James W. Kazura, James G. Beeson
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2021-12-01
Sraith:Frontiers in Immunology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fimmu.2021.775659/full
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