Enhancing the Total Terminal Galactosylation of CHO Cell-Derived TNF-α Blocker-IgG1 Monoclonal Antibody Using Time-Dependent Galactose Supplementation

<b>Background:</b> Recombinant monoclonal antibodies represent a vital category of biologics, constituting the largest class of molecules used to treat autoimmune disorders, cancers, rheumatoid arthritis, and other chronic conditions. The IgG1 subclass is the most potent among all the immunoglobulin...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Mallikarjuna Pulipeta, Pradeep Kumar Iyer, Rajendra Kumar Palakurthy, Narasimha Pullaguri, Rajasekhar Pinnamaneni, Srinivas Reddy Chilukuri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-06-01
coleção:	Biologics
Assuntos:	TNF-α blocker-IgG1 Chinese hamster ovary (CHO) cells galactose cell culture parameters galactosylation
Acesso em linha:	https://www.mdpi.com/2673-8449/5/2/16
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!