Enhancing the Total Terminal Galactosylation of CHO Cell-Derived TNF-α Blocker-IgG1 Monoclonal Antibody Using Time-Dependent Galactose Supplementation

<b>Background:</b> Recombinant monoclonal antibodies represent a vital category of biologics, constituting the largest class of molecules used to treat autoimmune disorders, cancers, rheumatoid arthritis, and other chronic conditions. The IgG1 subclass is the most potent among all the immunoglobulin...

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Päätekijät:	Mallikarjuna Pulipeta, Pradeep Kumar Iyer, Rajendra Kumar Palakurthy, Narasimha Pullaguri, Rajasekhar Pinnamaneni, Srinivas Reddy Chilukuri
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2025-06-01
Sarja:	Biologics
Aiheet:	TNF-α blocker-IgG1 Chinese hamster ovary (CHO) cells galactose cell culture parameters galactosylation
Linkit:	https://www.mdpi.com/2673-8449/5/2/16
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