Linker histone epitopes are hidden by in situ higher-order chromatin structure

Abstract Background Histone H1 is the most mobile histone in the cell nucleus. Defining the positions of H1 on chromatin in situ, therefore, represents a challenge. Immunoprecipitation of formaldehyde-fixed and sonicated chromatin, followed by DNA sequencing (xChIP-seq), is traditionally the method...

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Autores principales:	Vladimir B. Teif, Travis J. Gould, Christopher T. Clarkson, Logan Boyd, Enoch B. Antwi, Naveed Ishaque, Ada L. Olins, Donald E. Olins
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2020-06-01
Colección:	Epigenetics & Chromatin
Acceso en línea:	http://link.springer.com/article/10.1186/s13072-020-00345-9
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