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Drug Discovery in the Field of β-Lactams: An Academic Perspective

β-Lactams are the most widely prescribed class of antibiotics that inhibit penicillin-binding proteins (PBPs), particularly transpeptidases that function in peptidoglycan synthesis. A major mechanism of antibiotic resistance is the production of β-lactamase enzymes, which are capable of hydrolyzing...

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Autors principals: Lian M. C. Jacobs, Patrick Consol, Yu Chen
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2024-01-01
Col·lecció:Antibiotics
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Accés en línia:https://www.mdpi.com/2079-6382/13/1/59
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