Drug Discovery in the Field of β-Lactams: An Academic Perspective
β-Lactams are the most widely prescribed class of antibiotics that inhibit penicillin-binding proteins (PBPs), particularly transpeptidases that function in peptidoglycan synthesis. A major mechanism of antibiotic resistance is the production of β-lactamase enzymes, which are capable of hydrolyzing...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2024-01-01
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| coleção: | Antibiotics |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2079-6382/13/1/59 |
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