Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML

Abstract: Despite progress in research and treatment strategies for acute myeloid leukemia (AML), the prognosis for patients with AML, particularly for individuals aged >60 years and those with adverse risk factors, remains poor. Cellular receptors that affect cholesterol homeostasis may present a n...

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Autori principali:	Adam Y. Lin, Jonathan S. Rink, Eva Yang, Sara Small, Jessica J. Gerber, Taylor J. Zak, Jessica Altman, Yasmin Abaza, Leonidas C. Platanias, Leo I. Gordon, C. Shad Thaxton
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-11-01
Serie:	Blood Neoplasia
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2950328025000573
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